The immune system maintains homeostasis within human organisms and protects them from pathogenic threats. But sometimes it cannot provide this protection on its own, and vaccines may be necessary to ensure our health and survival. Immune functions can become dysregulated and result in autoimmune disease or multi-system damage. Pharmacological and genomic interventions may activate or modulate immune functions to prevent these outcomes. This Element is an analysis and discussion of some of the ethical implications of these interventions. After describing the main components of innate and adaptive immunity and how it might be enhanced, it considers the potential benefit and harm from vaccines against addiction and viruses, immunotherapy for cancer, neuroimmunomodulating agents to prevent or treat neurodevelopmental and neurodegenerative diseases, and gene editing of immunity to enable xenotransplantation and prevent infectious disease. The Element concludes with an exploration of a possible outcome of natural competition between humans and microbes.

This Element presents a careful analysis and discussion of the potential benefit and harm of interventions in the immune system.

Book Information
ISBN 9781009304597
Author Walter Glannon
Format Paperback
Page Count 75
Imprint Cambridge University Press
Publisher Cambridge University Press
Weight(grams) 147g
Dimensions(mm) 229mm * 152mm * 5mm