We examine how interacting genetic traits can affect the interpretation of case-control studies. Our model of personality reposes on three genetic traits: sanguinity (N), perfectionism (P) and aggression (A). The "complementary genes" for traits N and A are entangled: if one of the traits is absent, then the other must be present. This entanglement is the cause of infertility in certain combinations of NPA types. We examined hypothetical case-control studies with the use of Hardy-Weinberg methodology. Six different case-control studies were replicated in seven different representative populations. The computed results of each case-control study were highly dependent on the genetic composition of the representative population. When the condition present in the "case group" was genetically related to either trait N or A, there was a reciprocal difference induced in the other trait due to their entanglement, leading to possible confusion in interpretation of the results. Synopsis, Glossary, 25 ill., 80 pp.

Book Information
ISBN 9780359278879
Author A.M. Benis
Format Paperback
Page Count 80
Imprint Lulu.com
Publisher Lulu.com