Molecular Biology

Leading scientists in gene expression methodology and bioinformatics data analysis describe readily reproducible methods for measuring RNA levels in cells and tissues. The techniques presented include new methods for applying the Affymetrix GeneChip (R),...

This volume presents an assortment of traditional and emerging experimental procedures relevant to Schwann cell research. The chapters are divided into four parts. Part I contains protocols for in vitro culture, purification, and characterization of...

This volume provides the most cutting edge technologies related to the study of integrin activation and the characterization of their vast interactomes. Chapters detail protocols on experimental approached to quantify focal adhesion parameters, integrin...

When setting out to decide on the content of DNA Repair Protocols: Prokaryotic Systems, I was conscious of the need to portray the vast array of pathways and enzymatic activities that are part of the discipline of DNA repair. In addition to the classical...

Examines new research on the role of cholesterol in regulating ion channels and receptors and its effect on health Drawing together and analyzing all the latest research findings, this book explores the role of cholesterol in the regulation of ion...

The enormous advances made in molecular biology have allowed scientists to manipulate DNA with relative ease. This means that molecular biology has become a widely-used tool for answering scientific questions that may be quite unrelated to genetics and...

Systematics: A Course of Lectures is designed for use in an advanced undergraduate or introductory graduate level course in systematics and is meant to present core systematic concepts and literature. The book covers topics such as the history of...

This latest volume in the Harvey Lectures Series reflects "the evolution of physiology and physiological chemistry into biochemistry and the development of molecular biology from the roots of bacteriology and biochemistry" in the 20th and 21st...

Few scientists have the knowledge to perform the studies that are necessary to discover and characterize enzyme inhibitors, despite the vested interest the pharmaceutical industry has in this field. Beginning with the most basic principles pertaining to...

Cellular proteinases and their physiological role in normal and disease states have been the subject of great interest over recent decades. At present, specific protease inhibitors are exploited both as tools in unraveling the role of individual...

This volume deals with a multifunctional plasma and tissue protein, fibronectin, which participates in many significant biological and pathophysiological actions, presenting the information concerning structure and describing the interactions of...

Imagine scientists controlling the transmission of certain diseases through the genetic modification of mosquitoes. Eradicating harmful insects without the use of pesticides. Or increasing the fertility of some insects who in turn eat harmful arthropods...

From quantum theory to statistical mechanics, the methodologies of physics are often used to explain some of life's most complex biological problems. Exploring this challenging yet fascinating area of study, Molecular and Cellular Biophysics covers both...

The technical development of optical tweezers, along with their application in the biological and physical sciences, has progressed significantly since the demonstration of an optical trap for micron-sized particles based on a single, tightly focused...

Environmental Damage to DNA and the Protective Effects of Phytochemicals provides information on the toxicity of natural as well as synthetic chemicals in the living systems. These can lead to DNA damage and the emergence of serious consequences or...

Apologies but we at Booksplease don't have a full description for this book.Book InformationISBN 9780262042659Author K. Dane WittrupFormat HardbackPage Count 592Imprint MIT PressPublisher MIT Press LtdDimensions(mm) 229mm * 178mm * 32mm

The word stress is everywhere and highly overused. Everyone is stressed, it seems, all the time. Looking into the meaning of stress in the natural science and the humanities, this book explores cellular stress as cause of and in correlation with what...

For humankind, the most irreducible idea is the concept of life itself. In order to understand that life is essentially an infinite process, transmitted from generation to generation, this book takes the reader on a fascinating journey that unravels one...

This volume provides state-of-the-art techniques for studying various aspects of cholesterol homeostasis, including its uptake, synthesis and efflux from the cell, as well as its trafficking within the cell. Chapters also cover techniques for studying...

Mechanisms in Transcriptional Regulation provides a concise discussion of the fundamental concepts in transcription and its regulation. Covers RNA polymerases, transcriptional machinery, mechanisms of transcriptional activation, the histone code...

The book "Interaction of Coronavirus Disease 2019 with other Infectious and Systemic Diseases" elaborates on the pathogenesis, co-infection, and association of COVID-19 with other Infectious and Systemic Diseases. Moreover, this book explains...

This up-to-date book compiles both basic and advanced laboratory techniques of mammalian cell culture. It is divided into four major sections encompassing the basics of cell culture, nucleic acid and protein isolation, cell-staining techniques, and cell...

Ion channels generate bioelectricity. Recent findings have documented the biophysical properties, the structure, assembly and regulation, and function and dysfunction of nonclassical nervous system ion channels. This book reviews nonclassical ion channel...

New Findings Revolutionize Concepts of Gene FunctionEndogenous small RNAs have been found in various organisms, including humans, mice, flies, worms, fungi, and bacteria. Furthermore, it's been shown that microRNAs acting as cellular rheostats have the...

The Fundamentals of Scientific Research: An Introductory Laboratory Manual is a laboratory manual geared towards first semester undergraduates enrolled in general biology courses focusing on cell biology. This laboratory curriculum centers on studying a...

DNA Repair and Replication brings together contributions from active researchers. The first part of this book covers most aspects of the DNA damage response, emphasizing the relationship to replication stress. The second part concentrates on the...

Biological processes involving large macromolecular assemblies are thought to be a dynamic consequence of cooperativity and metastability. The folding of a peptide chain creates local environments from which "activity" can emerge. In the same way, the...

This unique volume reviews the beautiful architectures and varying mechanical actions of the set of specialized cellular proteins called molecular chaperones, which provide essential kinetic assistance to processes of protein folding and unfolding in the...

This book tells the story of a whole field of research which went disastrously wrong in many different directions when the wrong tools were used and the wrong targets aimed at, to solve a problem.It all started from the misinterpretation of Schellman's...

This book tells the story of a whole field of research which went disastrously wrong in many different directions when the wrong tools were used and the wrong targets aimed at, to solve a problem.It all started from the misinterpretation of Schellman's...

This invaluable book provides the first description of the diverse and fascinating functions of heme in life processes for a broad audience. It begins with an introduction to the intricate chemical properties of heme and the history of early observations...

Ever since the birth of molecular biology, the tantalizing possibility of treating disease at its genetic roots has become increasingly feasible. Gene therapy - though still in its infancy - remains one of the hottest areas of research in medicine. Its...

In the 17th century, Descartes put forth the metaphor of the machine to explain the functioning of living beings. In the 18th century, La Mettrie extended the metaphor to man. The clock was then used as the paradigm of the machine. In the 20th century,...

Ever since the birth of molecular biology, the tantalizing possibility of treating disease at its genetic roots has become increasingly feasible. Gene therapy - though still in its infancy - remains one of the hottest areas of research in medicine. Its...

'As an innovative treatment of scientific topics with philosophical undertones, this is an impressive work, Some may not be convinced by the arguments, but for scientists and philosophers alike the author presents a thesis worth exploring.'CHOICEThe book...

The book describes a common ground between the biology of life and the humanity of life without compromising either discipline. It attempts to bridge the gap between our 'two cultures' - the sciences and the humanities, as advocated by C P Snow fifty...

Synthetic Biology - A Primer gives a broad overview of the emerging field of synthetic biology and the foundational concepts on which it is built. It will be of interest to final year undergraduates, postgraduates and established researchers who are...

This book covers the current understanding of the role of activation-induced cytidine deaminase (AID) in the generation of antibody response to antigenic challenge. Since the discovery of AID, and the genetic demonstration of its role in somatic...

Synthetic Biology - A Primer (Revised Edition) presents an updated overview of the field of synthetic biology and the foundational concepts on which it is built. This revised edition includes new literature references, working and updated URL links, plus...

- Summarizes knowledge on proteostais- Focuses especially on the 26S/30S and 20S proteasome and immunoproteasome- Outlines the ways proteostasis malfunction contributes to diseases such as Alzheimer's, Parkinson's and Huntington's- Reviews the role of...