Immunology

During the late 1970's the application of hybridoma technology led to an explosion in the discovery and characterization of proteins expressed at the surface of hematopoietic cells. The understanding of T lymphocyte biology benefited enormously from this...

The idea for this volume was conceived during a discussion in the hallway at a conference in early 1990. "What is the best way to detect and define pluripotent hematopoietic stem cells?" was the question posed by Dr. Fritz Melchers. After...

After the discovery of the function of MHC molecules, namely to provide the context for T cell recognition of foreign antigens, in 1974 Zinkernagel and Doherty made the first drawing of MHC+X (Fig. 1 from Zinkernagel and Doherty, Nature, 251: 547, 1974)...

F. B. Michel Asthmology is the neologism I suggested for ideas which were acceptable at the begin- the title of a book published in 1981 on ning of the 20th century, and in particular bronchial asthma [4,5]. to Pasteur's concept of "one cause, one...

Proceedings of the NATO Advanced Study Institute on Immunotoxicology held at Acadia University, Wolfville, Nova Scotia, Canada, 14-23 July 1982Book InformationISBN 9783642697043Author P. W. MullenFormat PaperbackPage Count 164Imprint Springer-Verlag...

Primary immunodeficiency diseases (PIDs) are a heterogeneous group of inherited disorders characterized by different defects in the development and function of the immune system. This book aims to increase the clinical awareness and knowledge of...

This book, the last in a series of eight proceedings volumes, presents an up-to-date overview on immunology and inflammation based on a congress held in Budapest, Hungary in April 1998. It is divided into the following sections: Basic Mechanisms, Endo-...

This book is the result of the 3rd Wiggers Bernard Conference. The Wiggers Bernard Conferences, named after two great physiologists of the past, are biannual gatherings of the leaders in the field of shock. The meetings focus on specific areas of...

The good acceptance of this textbook is an indication that it has served its purpose. The present edition has been prepared in order to cover the main progress achieved in the five years that have elapsed since the first edition. The structure of the...

The book serves as a comprehensive resource for scientists and clinicians studying the role of non-coding RNAs in inflammation (viral infections, wound inflammation), human inflammatory diseases (i.e. rheumatoid arthritis, Crohn's disease, diabetes) and...

This volume provides a modern look on the age-old influenza infection and the preventive role of anti-influenza shots. Influenza pandemic outbreaks are unrelenting despite the growing understanding of the molecular basis of viral infection and its...

Hundreds of eponyms are used within the field of immunology—Petri dish, Crohn’s disease, Bence Jones protein, Kupffer cells, Freund's adjuvant, Ouchterlony immunodiffusion, to name just a few—but most of us don't know much about the individuals who gave...

This book integrates topics in basic research and clinical medicine as well as molecular and cell biology. It presents innovative advances in the field of immunodeficiency syndromes and viral/bacterial respiratory infections, including a novel hyperbaric...

This highly accessible textbook introduces readers to the development of viral vectors and discusses their application in veterinary vaccinology. It offers comprehensive information on the latest advances in this emerging research field, together with a...

This book brings awareness to a neglected condition that is nevertheless prevalent world-wide. Much focus is justly given to pulmonary tuberculosis, one of the key medical scourges of humanity, but this disease also often manifests itself in organs...

Antibodies tagged with fuorescent markers have been used in histochemistry for over 50 years. Although early applications were focused on the detection of microbial antigens in tissues, the use of immunocytochemical methods now has spread to include the...

The characterization of the cellular and molecular mechanisms that mediate inflammation provides a foundation that supports future studies that will de fine mechanisms more intimately. It encourages substantial optimism about the opportunities to...

It has been said that "never in the history of human progress has a better and cheaper method of preventing illness been developed than immunization". This is well illustrated by the WHO Expanded Programme on Immunization (EPI) which in...

This book provides basic, simple, and logical explanations for choices to be made to run the best Elispot possible. It allows the newcomer to truly understand the best options for specific protocol steps, reagents and materials, and provides even the...

This book introduces nanoparticles as a powerful platform for vaccine design. Current challenges in vaccine development are discussed and the unique advantages nanoparticles provide in overcoming these challenges are explored. The authors offer...

This second volume expands upon the previous edition with new research and objectives in immunoregulation and immune tolerance. Chapters cover topics ranging from new molecular and cellular mechanisms of tolerance; generation and characterization of mice...

Apologies but we at Booksplease don't have a full description for this book.Book InformationISBN 9781632413642Author Riley TateFormat HardbackImprint Hayle MedicalPublisher Hayle MedicalWeight(grams) 463g

During routine genetic screening of several immunoglobulin heavy chain congenic mouse strains in 1980, one of us (MB) was surprised to find that several mice in the C.B-17IIcr strain, which was being maintained in a specific-pathogen-free facility of the...

Upon infection the host needs to mount vigorous immune response against pathogen in order to successfully control its replication. However, once the infectious agent is controlled or eliminated, host cells need to signal the immune system to slow or...

This work is concerned with Cystic Fibrosis (CF), the most common fatal genetic disease in the Caucasian population. The decade of the 1980s was one of spectacular progress in understanding the genetic and molecu- lar basis of CF. The research...

Experimental and clinical evidence presented in this book illustrates that antibodies expressing different specificities can be very effective in preventing or reversing established transplant rejection. Moreover, the data leads us to hope that the use...

Accelerated Path to Cures provides a transformative perspective on the power of combining advanced computational technologies, modeling, bioinformatics and machine learning approaches with nonclinical and clinical experimentation to accelerate drug...

T-Helper Cells: Methods and Protocols presents a broad selection of cutting edge protocols that will enable the reader to capture the unique features of TH cells with tools developed for the isolation of TH cells from various tissues and subsequent...

A compendium of optimized methods to measure type I interferon efficacy as an antiproliferative or an antiviral agent. These cutting-edge techniques range from the simple to the highly complex and serve to illuminate the signaling cascades and the...

This volume serves as a follow-up to our previous book, MonoclonalAntibodies Hybridomas: A New Dimension in Biological Analyses. We continue the theme of monoclonal antibodies and their applications, attempting to cover some of the areas not covered in...

New information is developing so rapidly in the entire field of immunology that one is unable to remain abreast of all advancing fronts. In many cases, consider- able information has accumulated as the result of the efforts of many investigators, but the...

Sabine Stubler compares different proteasome isoforms and subtypes in terms of their transport and active site-related parameters applying an existing computational model. In a second step, the author extends this model to be able to describe the...

This volume provides a modern look on the age-old influenza infection and the preventive role of anti-influenza shots. Influenza pandemic outbreaks are unrelenting despite the growing understanding of the molecular basis of viral infection and its...

Peter A. Miescher The skin has always been one of the major targets to clinicians interested in immunology. Initially, the main focus was centred on allergic conditions such as contact hypersensitivity and urticeria. Gradually, the spectrum of...

Recent advances in the understanding of the major events that shape the immune recog nition system have been remarkable. The analysis of immunoglobulin (Ig) gene organization and Ig repertoire diversification in lower vertebrates has provided new insight...

This detailed volume provides methods to guide assay development, procedures designed to investigate the chemokine and glycosaminoglycan (GAG) networks, as well as their interactions, in a wide range of organs and tissues in disease and in health. The...

Georges Koehler was one of the most prominent German scientists of recent history. In 1984, at an age of 38, he received the Nobel Prize in Physiology or Medicine, together with N.K. Jerne and C. Milstein, for inventing the technique for generating...

This detailed book explores techniques for working in the field of immunogenetics, i.e. fundamental and translational research into the adaptive immune receptor repertoire. Many chapters are dedicated to lab protocols, bioinformatics, and...

This symposia series, founded in 1976, is devoted to the advancement and dissemination of knowledge in the field in immunology, particularly as it relates to the immune recognition and responses to protein and peptide antigens. Leading investigators are...

Enzyme-linked immunospot assay (ELISPOT) has been known for some time as a unique state-of-the-art technique for studying the cytokine-secreting activity of immune system cells, and it appears to be one of the fast growing applications in biomedical...