Worldwide, depression will be the single biggest cause of disability in the next 20 years. But treatment for it has not changed much in the last three decades. In the world of psychiatry, time has apparently stood still... until now.

In this game-changing book, University of Cambridge Professor Edward Bullmore reveals the breakthrough new science on the link between depression and inflammation of the body and brain. He explains how and why we now know that mental disorders can have their root cause in the immune system, and outlines a future revolution in which treatments could be specifically targeted to break the vicious cycle of stress, inflammation and depression.

The Inflamed Mind goes far beyond the clinic and the lab, representing a whole new way of looking at how mind, brain and body all work together in a sometimes misguided effort to help us survive in a hostile world. It offers insights into the story of Western medicine, how we have got it wrong as well as right in the past, and how we could start getting to grips with depression and other mental disorders much more effectively in the future.

'Suddenly an expert who wants to stop and question everything we thought we knew... This is a lesson in the workings of the brain far too important to ignore.' - Jeremy Vine, BBC

'Professor Bullmore explores how the current division between Psychiatry and the rest of medicine has developed and how we might change that. He puts forward a fascinating theory that attributes depression to inflammation rather than serotonin imbalance as has traditionally been thought. Whatever the truth, this book is a stimulating and interesting read.' - Wendy Burn, President Royal College of Psychiatrists

'A great read, this thought provoking book presents inflammation as the major driver of depression. A real page turner that raises important questions for us all, including, how we should practise medicine going forwards and can we restart Research and Development using this paradigm? Highly recommended. - Dame Sally Davies, Chief Medical Officer for England

About the Author
Professor Edward Bullmore BA MB PhD FRCP FRCPsych FMedSci trained in medicine at the University of Oxford and then at St Bartholomew's Hospital in London. After working as a physician in the University of Hong Kong, he trained as a psychiatrist at St George's Hospital, the Bethlem Royal and the Maudsley Hospital in London, and as a clinical scientist at the Institute of Psychiatry, King's College London. Since 1999, he has been a Professor of Psychiatry at the University of Cambridge, where he is now Head of the Department of Psychiatry and Director of the Wolfson Brain Imaging Centre in the Department of Clinical Neurosciences. He is an honorary consultant psychiatrist and Director of Research and Development for Cambridgeshire and Peterborough NHS Foundation Trust. Since 2005, he has also worked half-time for GlaxoSmithKline and is currently leading an academic-industrial consortium for the development of new anti-inflammatory drugs for depression. He is a world expert in neuroscience and mental health.

Reviews
'Suddenly an expert who wants to stop and question everything we thought we knew... This is a lesson in the workings of the brain far too important to ignore.' -- Jeremy Vine, BBC
'Professor Bullmore explores how the current division between Psychiatry and the rest of medicine has developed and how we might change that. He puts forward a fascinating theory that attributes depression to inflammation rather than serotonin imbalance as has traditionally been thought. Whatever the truth, this book is a stimulating and interesting read.' -- Wendy Burn, President Royal College of Psychiatrists
'A great read, this thought provoking book presents inflammation as the major driver of depression. A real page turner that raises important questions for us all, including, how we should practise medicine going forwards and can we restart Research and Development using this paradigm? Highly recommended. -- Dame Sally Davies, Chief Medical Officer for England
An important book, a hopeful book, for anyone who wants to think about depression in a new way. -- Tom Insel MD, Co-founder and President, Mindstrong Health
Erudite, enjoyable, and accessible... The Inflamed Mind confronts the reader with the converging revolutions in neuroscience and immunology that give rise to a new perspective about depression and its treatment. -- John H. Krystal, MD, Chair, Department of Psychiatry, Yale University School of Medicine
The Inflamed Mind is not only a dramatic breakthrough in our understanding of depression. It is an extraordinary exploration of what it is to be human. -- Matthew D'Ancona, author of 'Post Truth'
Compelling and highly readable. -- Professor Sir Colin Blakemore, University of London
Groundbreaking * The Times *
Fascinating * Today Programme, BBC *



Book Information
ISBN 9781780723723
Author Edward Bullmore
Format Paperback
Page Count 256
Imprint Short Books Ltd
Publisher Short Books Ltd
Weight(grams) 220g
Dimensions(mm) 196mm * 128mm * 24mm