The first protocols book, Free Radical and Antioxidant Protocols (1) was published in late 1998. Sections were divided into three parts, covering selected biochemical techniques for measuring oxidative stress, antioxidant (AOX) activity, and combined applications. In choosing the 40 methods to be included in that book, I realized there were considerably more of equal value than that which we could have presented in a single volume. To produce a comprehensive resource, this book and a third are being compiled to expand coverage of the field. A summary of papers (2) published on this important subject emphasizes the continuing rapid growth in oxidative stress investigations relating to our understanding of biochemical reactions, their relevance to pathophysiological mechanisms, how disease may arise, and how therapeutic intervention may be achieved(3). Although there is some overlap between the categories, the ana- sis shown below illustrates where current studies are concentrated and are almost evenly distributed between free radicals and AOX. Over the last 4 yr, there has been a 55% increase in the number of papers published in the area.
Reviews
"The book could be used effectively by experienced or novice basic science researchers or clinicians since the protocols are written clearly and concisely. Each of the chapters in the book gives specific instructions on how to prepare specimens for analysis. The chapters are clearly written, concise, and should be easy for anyone to follow. . .This book is intended and written as a guide to use in the laboratory. It would be quite useful for anyone wishing to assess many parameters of oxidative activities in biological specimens."-doody's Health Sciences Book Review Journal

"This is a superb book, a second volume edited by Donald Armstrong on this topic...There are 33 chapters in the 322 pages of this text therefore, each is commendably succinct and to the point. There are, unfortunately, far too many chapters to list all the topics covered, but it is extensive and amazing." - Free Radical Biology & Medicine




Book Information
ISBN 9780896038509
Author Donald Armstrong
Format Hardback
Page Count 322
Imprint Humana Press Inc.
Publisher Humana Press Inc.