This book comprehensively reviews the current state of clinical trial methods in multiple sclerosis treatment, providing investigators, sponsors and specialists with current knowledge of outcome measures and study designs for disease and symptom management. The status of the rapidly evolving field of disease-modifying drugs is presented, with emphasis on the most promising therapies currently being tested. Experts discuss disease and symptom management for MS subtypes, including neuromyelitis optica and pediatric MS. In addition, key scientific advances in MS pathology, genetics, immunology and epidemiology are presented. The fourth edition has been extensively revised, featuring more than 50% new material. All chapters have been substantially updated to provide current information on rapidly evolving topics and this volume contains 15 new chapters, reflecting the growth of the field in recent years. This book is an essential reference for practitioners caring for MS patients, investigators planning or conducting clinical trials, and clinical trial sponsors.

An indispensable reference for researchers, research sponsors and neurologists interested in the rapidly developing field of multiple sclerosis therapeutics.

About the Author
Jeffrey A. Cohen MD is Director of the Experimental Therapeutics Program at the Mellen Center for Multiple Sclerosis Treatment and Research, Department of Neurology, Neurological Institute, Cleveland Clinic, Cleveland, OH, USA. Richard A. Rudick MD is Director of the Mellen Center for Multiple Sclerosis Treatment and Research, Department of Neurology, Neurological Institute, Cleveland Clinic, Cleveland, OH, USA.


Book Information
ISBN 9780521766272
Author Jeffrey A. Cohen
Format Hardback
Page Count 770
Imprint Cambridge University Press
Publisher Cambridge University Press
Weight(grams) 2400g
Dimensions(mm) 282mm * 225mm * 41mm