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Geriatric Bioscience: The Link between Aging and Disease by David Hamerman

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Description

It is increasingly important for physicians who treat older persons, and for researchers on aging, to understand how molecular biology informs clinical expressions of aging and age-related conditions such as osteoporosis, diabetes, osteoarthritis, frailty, cancer, and dementia. Dr. David Hamerman translates basic scientific concepts into precepts of clinical practice and sheds light on the links among biology, natural aging, longevity, and disease. Exploring the connections between disease and the science behind it, Geriatric Bioscience addresses how mechanisms of inflammation, cytokine expression, and stress responses influence disease and how preventive gerontology in the practice of medicine could compress morbidity. Hamerman also discusses cutting-edge therapies such as cyclo-oxygenases, bisphosphonates, statins, cytokine inhibitors, and hormone therapies. Examining the science of geriatrics and converting its concepts into clinical applications, this groundbreaking work provides clinicians and researchers with a solid foundation for a greater understanding of the diagnosis, treatment, and prevention of age-related diseases as well as recommendations for promoting healthy aging.

One of the greatest challenges facing biologists in the twenty-first century is understanding how the aging process predisposes organisms to the host of pathologies known as age-related disease. This book describes the essential elements of this challenge and is an important and intelligent addition to the gerontology literature. -- Judith Campisi, Ph.D., Buck Institute for Age Research, Lawrence Berkeley National Laboratory This book is a landmark achievement in presenting a perspective of the biology of aging that is linked to the expression of many diseases affecting older persons. -- Ronald A. DePinho, M.D., Harvard Medical School, Director, Center for Applied Cancer Science, Dana-Farber Cancer Institute In this remarkable volume, David Hamerman presents the many exciting advances in our knowledge of the biology of aging and clearly relates them to clinical geriatrics, a link we all need and can use. -- T. Franklin Williams, M.D., University of Rochester, former Director, National Institute on Aging

About the Author
David Hamerman, M.D., is Distinguished University Professor of Medicine at the Albert Einstein College of Medicine, founder of the Division of Geriatrics at Montefiore Medical Center, and editor of Osteoarthritis: Public Health Implications for an Aging Population, also published by Johns Hopkins.

Reviews
Hamerman leads the advanced and careful reader to a better understanding of the relationships between the biology of aging and the emergence of aging-related diseases. Choice 2008 A unique presentation based on the author's many decades of research and experience in the science of aging. It is extremely well documented with more than a thousand references and a helpful reference... an important source of information from an expert. -- Dr. Steven Schwartz Riverdale Press 2008 The nexus between obesity, heart disease, diabetes, cancer, and Alzheimer's disease is tantalizing. It takes the hand of a master to synthesize so much material and give a unified overarching view of the relationship between aging and disease. This skillful hand is seen in the smooth flow of the book and a most pleasurable style of writing. -- David O. Staats Doody's Review Service 2008 A must-read for clinicians providing primary care in geriatrics -- Laura J. Niedernhofer Journal of Clinical Investigation 2008 An inspiring, concise, comprehensive, and stimulating primer of the field for aspiring gerontologists, geriatricians, and other physicians who will care for elderly persons. -- William B. Hazzard, MD JAMA 2008 The depth of knowledge presented is astounding... It is a must read for young and in-training geriatricians. -- Dr. Denise Zwahlen-Minton Pharos 2009 I found much of interest in the collection. -- John E. Morley Ageing and Society 2008



Book Information
ISBN 9780801886928
Author David Hamerman
Format Hardback
Page Count 316
Imprint Johns Hopkins University Press
Publisher Johns Hopkins University Press
Weight(grams) 567g
Dimensions(mm) 229mm * 152mm * 25mm

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