Transcription, or the process by which DNA produces RNA, is a central aspect of gene expression. Transcription factors regulate transcription during development and in disease states. As such, it is critical for researchers to gain a good understanding of the relationship between the structure of various families of transcription factors and their function, as well as roles in human disease. Since publication of the Fourth Edition, there have been major advances, notably in the areas of chromatin remodeling and genome-scale analyses. This complete update includes all new coverage of the latest developments, from enabling genomic technologies to studies on the importance of post-translational modifications beyond phosphorylation events.

Provides a clear and concise descriptio of transcription factors and their role in gene regulation

Book Information
ISBN 9780123739834
Author David S. Latchman
Format Hardback
Page Count 488
Imprint Academic Press Inc
Publisher Elsevier Science Publishing Co Inc
Weight(grams) 1180g