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Epigenetics: Linking Genotype and Phenotype in Development and Evolution by Benedikt Hallgrimsson 9780520267091

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Description

Illuminating the processes and patterns that link genotype to phenotype, "Epigenetics" seeks to explain features, characters, and developmental mechanisms that can only be understood in terms of interactions that arise above the level of the gene. With chapters written by leading authorities, this volume offers a broad integrative survey of epigenetics. Approaching this complex subject from a variety of perspectives, it presents a broad, historically grounded view that demonstrates the utility of this approach for understanding complex biological systems in development, disease, and evolution. Chapters cover such topics as morphogenesis and organ formation, conceptual foundations, and cell differentiation, and together demonstrate that the integration of epigenetics into mainstream developmental biology is essential for answering fundamental questions about how phenotypic traits are produced.

About the Author
Benedikt Hallgrimsson, Professor in the Department of Cell Biology and Anatomy at the University of Calgary, is coeditor of Variation: A Central Concept in Biology and of Advanced Imaging in Biology and Medicine: Technology, Software Environments, Applications. Brian K. Hall is University Research Professor Emeritus at Dalhousie University. His latest book is Evolution: Principles and Processes.

Reviews
"Eloquent, comprehensive, and insightful." -- Marcelo R. Sanchez-Villagra Evolution & Development "Epigenetics will go a long way towards making the reader re-evaluate any ideas that the evolution of variation is purely due to small genetic change." -- Brian Livingstone Linnean Society Biological Journal "This book is an invaluable contribution for understanding the intricacies of evolutionary processes as well as for devising interventional approaches to enhance healthy life span in humans." -- Diddahally R Govindaraju Evolution: Education and Outreach



Book Information
ISBN 9780520267091
Author Benedikt Hallgrimsson
Format Hardback
Page Count 472
Imprint University of California Press
Publisher University of California Press
Weight(grams) 1089g
Dimensions(mm) 254mm * 178mm * 25mm

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