Molecular Biology

This volume describes high-throughput approaches to a series of robust, established methodologies in molecular genetic studies of population samples. Such developments have been essential not only to linkage and association studies of single-gene and...

The presented information reflects a state-of-the-art summary of the pleiotropic effects of IL-10 in vitro and in vivo and will contribute to our understanding of the role of ILj-10 in the immune system and its potential clinicial utility in the near...

There has been recent rapid progress in the transformation of plants with foreign DNA, making use either of the natural routes of genetic invasion that viruses and bacteria have developed, or of chemical, mechanical and electrical tricks to make plant...

Identification of differentially expressed genes is one of the major challenges in molecular biology. Several techniques allow the cloning of such sequences. However, methods such as RNA subtraction or differential hybridization are time-consuming and...

Parasitic diseases still affect millions of people every year, especially in the tropics, causing considerable morbidity or death. Such infections within livestock are probably an even bigger problem, leading to poorer productivity, condemna tion of...

Apoptosis plays a central role in the regulation of cell proliferation. Disruption of this control mechanism may cause serious human diseases such as encephalomyelitis and cancer. Thus, understanding of the molecular mechanisms of apoptotic cell death...

This book constitutes the first comprehensive discussion and collection of facts and functions of unconventional secretory pathways, some of which are of importance in human disease and pathology. The function of ABC transporters in these processes is...

Among all cellular RNA species of the three main types, ribosomal RNA, transfer RNA or messenger RNA, be they from prokaryotic or eukaryotic organisms, the prokaryotic mRNA is unique in that it has no precursor and is synthesized in the same mature form...

This monograph explores the relationships between cell signaling and the cytoplasmic cytoskeleton in fundamental cell processes, thus bridging the gap between two very active aspects of molecular cell biology. It covers the two main - and reciprocal -...

In the last few years there have been tremendous advances in the understanding of signals and signalling pathways that operate at the cellular level and lead to developmental processes. In 27 chapters, this volume investigates the cellular and molecular...

For decades this virus system has served--and continues to do so--to pioneer investigations on the molecular biology, biochemistry and genetics of mammalian cell systems. This three volume work presents an up-to-date account of recent basic research in...

Modern cell biology has brought improvements in therapy for advanced malignant diseases through immunomodulation, hematopoietic stem cell transplantation, and other advanced techniques. Collected here are selected papers from the Fifth International...

During the last decade and a half, studies of evolution and variation have been revolutionized by the introduction of the methods and concepts of molecular genetics. We can now construct reliable phylogenetic trees, even when fossil records are missing,...

Biological functions are almost exclusively attributed to macromolecules, i.e. nucleic acids, proteins and polysaccharides. To gain their complete functional activities these biomolecules have to associate with the nuclear matrix, the cytoskeleton and...

Apologies but we at Booksplease don't have a full description for this book.Springer Book ArchivesBook InformationISBN 9783642666285Author T. Arpa-GabarroFormat PaperbackPage Count 178Imprint Springer-Verlag Berlin and Heidelberg GmbH & Co. KPublisher...

Interdependence between species is a law of nature. The degree of this interdependence is vividly evident in the plant-microbial world. Indeed, there is no axenic plant in nature and one finds various forms of interac tions between these two kingdoms...

Carbohydrate as the primary product of photosynthesis has a vital role in the maintenance of life on this planet. Until relatively recently, interest in complex carbohydrates focussed on their structural role in the extracellular matrix/ cell wall of...

Recent years have witnessed an explosion of knowledge lea- ding to a molecular understanding of the mechanisms of ac- tion of calcium on excitation and contraction coupling and its role in the regulation of contractility. This book highlights the most...

normal and pathological mineralization in vertebrates but also with the interesting problems involved in the formation of in tracellular deposits of calcium oxalate in plants. Here cal cium carbonate and silica may also be involved in the mineral ization...

In modern scientific investigation the fields of biochemistry, molecular biology, and morphology comprise an indivisible area of study. The present book results from the cooperation of a bioehernist and morphologists: the revision and unified treatment...

Presented here is an analysis of plant development and plant metabolism using the tools of genetics and molecular biology, such as mutant analysis, mutation tagging, mapping using polymorphic characters and basic molecular biology techniques. Studies...

Different aspects of cytogenetics, such as the molecular structure of eukaryotic chromosomes, computerized analyses of chromosomes, evolution of karyotypes, chromosomes and cancer, chromosomes in genetic toxicology, and chromosomal aberrations (-...

Cell culture techniques allow a variety of molecular and cell biological questions to be addressed, offering physiological conditions whilst avoiding the use of laboratory animals. In addition to basic techniques, a wide range of specialised practical...

"Recent studies have discovered new known and characterized cytokines, allowing for advancement in miniaturization of micro-analytical methods as well as the extensive development of bio-informatics and nanotechnology. These advancements have...

Connexins: A Guide is a practical and valuable reference and text covering a wide scope of information about the connexin family of membrane channel proteins. The editors and contributing authors intend for this cutting-edge work to be informative to...

Apologies but we at Booksplease don't have a full description for this book.Book InformationISBN 9783039213894Author Robert M Brosh JrFormat PaperbackPage Count 368Imprint Mdpi AGPublisher Mdpi AGWeight(grams) 170g

The purpose of Applications Therapeutic of Ribozymes is to provide an overview of the utility of ribozymes to selectively inhibit the expression of RNA. The ribozyme applications appearing in this book should benefit not only those experienced in...

Whether the question is one of basic cell survival, or whether it is being used to correlate cell number to some other factor such as matrix synthesis, an estimate of cell viability is universally required. In Mammalian Cell Viability: Methods and...

To prepare synchronized cells representing different stages of the cell cycle has been a great challenge for researchers across the globe. In Cell Cycle Synchronization: Methods and Protocols, experts in the field supply detailed protocols providing...

The interdisciplinary field of molecular systems biology aims to understand the behavior and mechanisms of biological processes composed of individual molecular components. As we gain more qualitative and quantitative information of complex intracellular...

Microtubules are at the heart of cellular self-organization, and their dynamic nature allows them to explore the intracellular space and mediate the transport of cargoes from the nucleus to the outer edges of the cell and back. In Microtubule Dynamics:...

Aimed at both beginners and experienced researchers unfamiliar with the technique, this book provides a concise and easy-to-understand guide to using immunohistochemistry. It identifies the proper place and purpose of each component of...

Chromosomes have structure, determined by the interactions of proteins with DNA, and chromosomes have functions, in particular, replication of DNA and transcription of messenger RNA. Chromosome structure and function are not separate topics, since...

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This volume of the series Springer Briefs in Space Life Sciences explains the physics and biology of radiation in space, defines various forms of cosmic radiation and their dosimetry, and presents a range of exposure scenarios. It also discusses the...

This book on cardiac extracellular matrix (ECM) features three sections, Fundamental Science, Pre-Clinical and Translational Science, and Clinical Applications. In the Fundamental Science section, we will cover the spectrum of basic ECM science from...

In 1898 Camillo Golgi reported his newly observed intracellular structure, the apparato reticolare interno, now universally known as the Golgi Apparatus. The method he used was an ingenious histological technique (La reazione nera) which brought him fame...

Apologies but we at Booksplease don't have a full description for this book.Book InformationISBN 9781789841336Author Charalampos ProestosFormat HardbackPage Count 88Imprint IntechOpenPublisher IntechOpen

This volume details comprehensive protocols and methodologies to assess mitochondrial bioenergetics and dynamics in different tissues and cells involving health and pathological states. Chapters guide readers through methods for assessment of the energy...

This detailed volume explores the large research area of Notch signaling studies in a variety of model organisms. The collected research methods and protocols include the dissection of Notch functional sites, Notch regulators, Notch activity reporters...