General

Theory of Drug Development presents a formal quantitative framework for understanding drug development that goes beyond simply describing the properties of the statistics in individual studies. It examines the drug development process from the...

Statistical Geoinformatics for Human Environment Interface presents two paradigms for studying both space and interface with regard to human/environment: localization and multiple indicators. The first approach localizes thematic targets by treating...

THE COMPLETE COLLECTION NECESSARY FOR A CONCRETE UNDERSTANDING OF PROBABILITY Written in a clear, accessible, and comprehensive manner, the Handbook of Probability presents the fundamentals of probability with an emphasis on the balance of theory,...

Economic evaluation has become an essential component of clinical trial design to show that new treatments and technologies offer value to payers in various healthcare systems. Although many books exist that address the theoretical or practical aspects...

Easy-to-Use Reference and Software for Statistical Modeling and TestingHandbook of Statistical Distributions with Applications, Second Edition provides quick access to common and specialized probability distributions for modeling practical problems and...

Many practitioners in the pharmaceutical industry are still largely unfamiliar with benefit-risk assessment, despite its growing prominence in drug development and commercialization. Helping to alleviate this knowledge gap, Benefit-Risk Assessment in...

Sensory Evaluation of Sound provides a detailed review of the latest sensory evaluation techniques, specifically applied to the evaluation of sound and audio. This three-part book commences with an introduction to the fundamental role of sound and...

This book sketches some of the legal doctrines that underlie discrimination litigation. It describes and probes frequently seen statistical methods. The book also describes the more or less standard methods being brought into United States Supreme Court...

Medical Product Safety Evaluation: Biological Models and Statistical Methods presents cutting-edge biological models and statistical methods that are tailored to specific objectives and data types for safety analysis and benefit-risk assessment. Some...

Statistical Analysis of Human Growth and Development is an accessible and practical guide to a wide range of basic and advanced statistical methods that are useful for studying human growth and development. Designed for nonstatisticians and statisticians...

This book gives an introduction to the theoretical and computational fluid dynamics of a compressible fluid. It focuses on the basic assumptions and the formulation of the theory of compressible flow as well as on the methods of solving problems.About...

Making statistical modeling and inference more accessible to ecologists and related scientists, Introduction to Hierarchical Bayesian Modeling for Ecological Data gives readers a flexible and effective framework to learn about complex ecological...

Since their introduction, hierarchical generalized linear models (HGLMs) have proven useful in various fields by allowing random effects in regression models. Interest in the topic has grown, and various practical analytical tools have been developed...

The first book to examine weakly stationary random fields and their connections with invariant subspaces (an area associated with functional analysis). It reviews current literature, presents central issues and most important results within the area. For...

Models for Dependent Time Series addresses the issues that arise and the methodology that can be applied when the dependence between time series is described and modeled. Whether you work in the economic, physical, or life sciences, the book shows you...

State-of-the-Art Methods for Drug Safety AssessmentResponding to the increased scrutiny of drug safety in recent years, Quantitative Evaluation of Safety in Drug Development: Design, Analysis and Reporting explains design, monitoring, analysis, and...

Written specifically for biotechnology scientists, engineers, and quality professionals, this book describes and demonstrates the proper application of statistical methods throughout Chemistry, Manufacturing, and Controls (CMC). Filled with case studies,...

The normal distribution is widely known and used by scientists and engineers. However, there are many cases when the normal distribution is not appropriate, due to the data being skewed. Rather than leaving you to search through journal articles,...

This book reviews the state-of-the-art advances in skew-elliptical distributions and provides many new developments in a single volume, collecting theoretical results and applications previously scattered throughout the literature. The main goal of this...

Technological improvements continue to push back the frontier of processor speed in modern computers. Unfortunately, the computational intensity demanded by modern research problems grows even faster. Parallel computing has emerged as the most successful...

Bayesian Inference for Partially Identified Models: Exploring the Limits of Limited Data shows how the Bayesian approach to inference is applicable to partially identified models (PIMs) and examines the performance of Bayesian procedures in partially...

Since 1945, "The Annual Deming Conference on Applied Statistics" has been an important event in the statistics profession. In Clinical Trial Biostatistics and Biopharmaceutical Applications, prominent speakers from past Deming conferences present novel...

Those who work in allied health professions and education aim to make people's lives better. Often, however, it is hard to know how effective this work has been: would change have occurred if there was no intervention? Is it possible we are doing more...

Preeminent Experts Update a Well-Respected BookTaking into account the regulatory and scientific developments that have occurred since the second edition, Design and Analysis of Bioavailability and Bioequivalence Studies, Third Edition provides a...

Using real data sets throughout, Survival Analysis in Medicine and Genetics introduces the latest methods for analyzing high-dimensional survival data. It provides thorough coverage of recent statistical developments in the medical and genetics fields...

Classroom tested and the result of over 30 years of teaching and research, this textbook is an invaluable tool for undergraduate and graduate data analysis courses in environmental sciences and engineering. It is also a useful reference on modern digital...

Praise for the First Edition "The obvious enthusiasm of Myers, Montgomery, and Vining and their reliance on their many examples as a major focus of their pedagogy make Generalized Linear Models a joy to read. Every statistician working in any area of...

An accessible book on sampling techniques with emphasis on and illustrations from surveys of human populations. Explains how to design and execute valid samples of moderate dimensions and difficulty, avoid selection biases and how to become more adept at...

A precise and accessible presentation of linear model theory, illustrated with data examples Statisticians often use linear models for data analysis and for developing new statistical methods. Most books on the subject have historically discussed...

There is a growing interest in developing register-based surveys; that is surveys based upon already available administrative data. Since huge amounts of such data are generated within various administrative systems, the opportunity exists to use the...

Item Response Theory clearly describes the most recently developed IRT models and furnishes detailed explanations of algorithms that can be used to estimate the item or ability parameters under various IRT models. Extensively revised and expanded, this...

Carefully designed for use by clinical and pharmaceutical researchers and scientists, Handbook of Regression Analysis and Modeling explores statistical methods that have been adapted into biological applications for the quickly evolving field of...

Emphasizing concepts rather than recipes, An Introduction to Statistical Inference and Its Applications with R provides a clear exposition of the methods of statistical inference for students who are comfortable with mathematical notation. Numerous...

By discussing statistical concepts in the context of transportation planning and operations, Transportation Statistics and Microsimulation provides the necessary background for making informed transportation-related decisions. It explains the why behind...

Providing an interface between dry-bench bioinformaticians and wet-lab biologists, DNA Methylation Microarrays: Experimental Design and Statistical Analysis presents the statistical methods and tools to analyze high-throughput epigenomic data, in...

DNA evidence is widely used in the modern justice system. Statistical methodology plays a key role in ensuring that this evidence is collected, interpreted, analysed and presented correctly. This book is a guide to assessing DNA evidence and presenting...

Presents a useful new technique for analyzing the extreme-value behaviour of random fields Modern science typically involves the analysis of increasingly complex data. The extreme values that emerge in the statistical analysis of complex data are often...

This volume describes how to conceptualize, perform, and critique traditional generalized linear models (GLMs) from a Bayesian perspective and how to use modern computational methods to summarize inferences using simulation. Introducing dynamic modeling...

The past 10 years have brought amazing changes to the technologies used to turn remotely sensed data into maps. As a result, the principles and practices necessary for assessing the accuracy of those maps have also evolved and matured. This third edition...

This book describes a systematic methodology for formulating mixed-ingredient products so that they perform to particular standards, providing scientists and engineers with a fast track to the implementation of the methodology. Examples from a wide...