Liver disease is a widespread and increasing problem throughout the world, however little is published on how different types and degrees of liver dysfunction affect the body's ability to handle medicines."Drugs and the Liver" is designed to assist practitioners in making pragmatic choices for their patients. It aims to: enable the practitioner to assess liver function using biochemical markers, other tests, signs, symptoms and disease knowledge; identify which pharmacokinetic and pharmacodynamic parameters of a drug are likely to be affected by different types of liver disease; and consider the impact of a drug's side effects on a patient with liver disease.This practical guide covers background information on liver function, the principles of drug use in liver disease and includes a section of worked examples of commonly asked questions. It will be invaluable to clinical pharmacists and anyone making medicine choices in patients with liver impairment.
Reviews

'For those pharmacists involved in medication reviews, interpretation of liver function test results is an essential part of the process. This book provides an excellent explanation of each parameter and the limitations of using the results alone when assessing the degree of liver function.'
Jackie Smith, a pharmaceutical advisor, Chemist and Druggist, October 2008

-- Jackie Smith * Chemist and Druggist *

'This book combines all pertinent issues relating to liver dysfunction and medication use in one reference. The authors and contributors have done an excellent job to make the book a practical tool that can be used by clinicians when making therapeutic choices rather than merely presenting pharmacokinetic principles and expected alterations in liver disease.'
Sharya Vaughan Bourdet, PharmD BCPS, The Annals of Pharmacotherapy Vol. 42, July/August 2008

-- Sharya Vaughan Bourdet * The Annals of Pharmacotherapy *

'The book is written primarily for pharmacist clinicians, but it serves as a useful review for anyone who has an interest in drug metabolism and liver function...the thorough but easy to understand review of the liver anatomy and function is a highlight. This is a good read for those who need to brush up on these topics.'
Patrick J. McDonnell, Temple University School of Pharmacy. Doody Enterprises, Inc. April 2008

-- Patrick J. McDonnell * Doody Enterprises *



Book Information
ISBN 9780853697107
Author Miss Penny North-Lewis
Format Paperback
Page Count 344
Imprint Pharmaceutical Press
Publisher Pharmaceutical Press
Weight(grams) 513g
Dimensions(mm) 234mm * 156mm * 21mm