Cell Movement in Health and Disease brings the several scientific domains related to the phenomena together, establishing a consistent foundation for researchers in this exciting field. The content is presented in four main section. The first explores the foundations of Cell Movement, including overviews of cellular structure, signaling, physiology, motion-related proteins, and the interface with the cellular membrane. The second part covers the biological aspects of cellular movement, starting with chemical and mechanical sensing, describing the types of cell movement, mechanics at cell level, cell physiology, collective behavior, and the connections with the extracellular matrix. The following chapters provide an overview of the molecular machinery involved and cell-type specific movement. The third part of the book is dedicated to the translational aspects of cell movement, highlighting the key conditions associated with cell movement dysfunction, like cell invasion in cancer, wound healing, developmental issues, neurological dysfunctions, and immune response. The final part of the book covers key methods and modeling tools for cell movement research, including predictive mathematical models, in vitro and in vivo methods, biophysical and bioinformatics tools. Cell Movement in Health and Disease is the ideal reference for scientists from different backgrounds converging to expand the understanding of this key cellular process. Cellular and molecular biologists will gain a better understanding of the physical principals operating at cellular level while biophysicist and biomedical engineers will benefit from the solid biology foundation provided by the book.

About the Author
Dr. Michael Schnoor received his master's degree in chemistry from the Institute of Biochemistry, Westphalian Wilhelms University, Munster, Germany and PhD in Biochemistry from the same institution. His post-doc studies with emphasis on immunology and mucosal inflammation was developed at the Emory University, Atlanta, GA, USA. He currently Principal Investigator at the Department for Molecular Biomedicine, Center for Investigation and Advanced Studies, Mexico City, Mexico. His research evolves around inflammation, actin, and actin-binding molecules, endothelial cell contact stability and leukocyte transmigration. Dr. Schnoor has published over 50 articles in peer-review journals and presented in conferences around the world. For his research he received awards from the American Society for Investigative Pathology and is funded by sources both in Germany and Mexico. Dr. Leimiao Yin is currently Professor at the Shanghai University of Traditional Chinese Medicine, Shanghai, China. He is Guest Associate Editor for the Cell Adhesion and Migration special issue from Frontiers in Cell and Developmental Biology. He has published over 40 research articles in international peer-review journals. Sean Sun is a vice-chair and professor in the Department of Mechanical Engineering at the Whiting School of Engineering and at the Physical Science-Oncology Center under INBT. His research improves on current knowledge of cell motility, molecular motors, proteins and membranes, statistical mechanics, and theoretical biomechanics, and biophysics. Dr. Sun was a 2017 inductee as an AIMBE Fellow, for outstanding contributions to our quantitative understanding of cell mechanics, cell motility and force generation mechanisms in live cells. He received his BS from Penn State in 1994 and PhD in theoretical chemistry from the University of California, Berkley, in 1998.


Book Information
ISBN 9780323901956
Author Michael Schnoor
Format Paperback
Page Count 384
Imprint Academic Press Inc
Publisher Elsevier Science & Technology
Weight(grams) 1060g