Until the early 1960s, cancer treatment consisted primarily of surgery and radiation therapy. Most practitioners then viewed the treatment of terminally ill cancer patients with heroic courses of chemotherapy as highly questionable. The randomized clinical trials that today sustain modern oncology were relatively rare and prompted stiff opposition from physicians loath to assign patients randomly to competing treatments. And yet today these trials form the basis of medical oncology. How did such a spectacular change occur? And how did medical oncology pivot from a nonentity and, in some regards, a reviled practice to the central position it now occupies in modern medicine? In "Cancer on Trial" Peter Keating and Alberto Cambrosio explore how practitioners established a new style of practice, at the center of which lies the clinical cancer trial. Far from mere testing devices, these trials have become full-fledged experiments that have redefined the practices of clinicians, statisticians, and biologists. Keating and Cambrosio investigate these trials and how they have changed since the 1960s, all the while demonstrating their significant impact on the progression of oncology. A novel look at the institution of clinical cancer research and therapy, this book will be warmly welcomed by historians, sociologists, and anthropologists of science and medicine, as well as clinicians and researchers in the cancer field.

About the Author
Peter Keating is professor of history at the Universite du Quebec a Montreal. Alberto Cambrosio is professor in the Department of Social Studies of Medicine at McGill University. Together, they are the authors of Exquisite Specificity: The Monoclonal Antibody Revolution and Biomedical Platforms: Realigning the Normal and the Pathological in Late Twentieth-Century Medicine.

Reviews
"This remarkable book charts the emergence of a clinical field - medical oncology - for which experimental protocols have become routinized as a form of normal practice. Cancer on Trial will make a lasting contribution to the sociology of scientific knowledge, the history of clinical practice, and the understanding of the networked basis of biomedical research." (Jeremy A. Greene, Harvard University)"



Book Information
ISBN 9780226428918
Author Peter Keating
Format Hardback
Page Count 424
Imprint University of Chicago Press
Publisher The University of Chicago Press
Weight(grams) 765g
Dimensions(mm) 24mm * 16mm * 3mm