A Practical Guide to the Histology of the Mouse provides a full-colour atlas of mouse histology. Mouse models of disease are used extensively in biomedical research with many hundreds of new models being generated each year. Complete phenotypic analysis of all of these models can benefit from histologic review of the tissues.

This book is aimed at veterinary and medical pathologists who are unfamiliar with mouse tissues and scientists who wish to evaluate their own mouse models. It provides practical guidance on the collection, sampling and analysis of mouse tissue samples in order to maximize the information that can be gained from these tissues. As well as illustrating the normal microscopic anatomy of the mouse, the book also describes and explains the common anatomic variations, artefacts associated with tissue collection and background lesions to help the scientist to distinguish these changes from experimentally- induced lesions.

This will be an essential bench-side companion for researchers and practitioners looking for an accessible and well-illustrated guide to mouse pathology.

• Written by experienced pathologists and specifically tailored to the needs of scientists and histologists
• Full colour throughout
• Provides advice on sampling tissues, necropsy and recording data
• Includes common anatomic variations, background lesions and artefacts which will help non-experts understand whether histologic variations seen are part of the normal background or related to their experimental manipulation

About the Author
Cheryl L Scudamore is currently Head of Pathology at Mary Lyon Centre, MRC Harwell and an Honorary Professor in Experimental Pathology at the Royal Veterinary College. She has worked extensively as a pathologist in academia and industry in the UK and is known for her interest in and promotion of postgraduate training in laboratory animal pathology and histological techniques.

Reviews

"Overall this is a clearly written and well illustrated guide to the histology of the mouse, but also goes a step further by providing information on selected techniques, background pathology, potential artefacts and additional procedures associated with the examination of this commonly used laboratory species. It should prove a useful reference for any scientist examining mice as part of their work or research." (BTS News, 1 September 2014)

"The hardcover earns a recommendation as a practical addition to a reference library through the text's succinct coverage of a complex topic to illustrate the basic histopathology of the mouse." (Veterinary Pathology, 31 October 2014)

Book Information
ISBN 9781119941200
Author Cheryl L. Scudamore
Format Hardback
Page Count 256
Imprint Wiley-Blackwell
Publisher John Wiley and Sons Ltd
Weight(grams) 717g
Dimensions(mm) 254mm * 193mm * 18mm